Need advice on fixing a stripped screw hole in an old cabinet door.

I'm trying to restore an old cabinet I found, but one of the hinge screw holes is completely stripped out. The wood is a bit soft, so just using a larger screw doesn't seem like it will hold for long.

I’ve heard about the "toothpicks and wood glue" trick, but does that actually hold up over time for a heavy door? Or should I look into using a wood filler or a dowel instead? Any tips from people who have dealt with older furniture would be greatly appreciated!